Le mishini yokukhipha isetshenziswa ngokuvamile embonini yezemithi, yokunakekelwa kwempilo, nezimonyo ukuze kukhishwe ama-compounds asebenzayo noma amafutha abalulekile ezitshalweni zokwelapha noma amakhambi, izimbali, amaqabunga, njll. Enqubweni yokukhipha, uhlelo lwe-vacuum lusiza ukushintshwa kwe-nitrogen ukuze kuqinisekiswe. akukho ukusabela kwe-oxidation ezintweni.